If you've been in acting for any amount of time, you must have SOME kind of accent or dialect that you can employ at will. Some of us have French, others love British, or maybe you've mastered the southern states, or have made a dive into the masses of Asia.
The accent doesn't matter. What does matter is trying it out with your material. Just reading it through with a different accent will provide you with insight into other ways to address the scene. This is especially useful when you feel like you're getting into a rut and are doing the scene the same way over and over again.
Doing it like your from Mississippi will change that for sure. The emphasis will be on different syllables, different parts of the sentence, you may even find a piece in there where there's a bit of humor that you didn't catch before. It a great, great discovery tool.
And hey it's pretty damn fun too.